Something must be changing in the guides locations before they reach Edit Guides. This means that either the scalp mesh topology (number/positions of faces) changes or distribution parameters for guides are changing. I would advise to use the "Remember" button in the guides from surface modifier to ensure that guides are cached with the scene and are not re-generated. This should take care of the problem.

Marsel Khadiyev (Software Developer, EPHERE Inc.)

Howdy Ramous,

Your right we need to add Remember into the Guides from Surface docs. It is in the Hair from Guides docs were it is most used. This option is really used more for remembering the root positions during rendering. It might work for changing topology of a mesh but its not a common use.

It is most advised that your topology does not change under the hair. This similar to a lot of modifiers in max like Skin, Morph, edit poly etc. If you change the underlying topology you invalidate the modifiers above. I thought I went over this in the OX 101 videos but I will double check and add to the docs too.

Thanks!